Clinical and cortical decline in the aphasic variant of Alzheimer’s disease
By ACA |
Primary progressive aphasia (PPA) displays variable progression trajectories that require further elucidation.
Read More Learnings about the complexity of extracellular tau aid development of a blood-based screen for Alzheimer’s disease
By ACA |
The tau protein plays a central role in Alzheimer's disease (AD), and there is huge interest in measuring tau in ...
Read More Human stem cell–derived monocytes and microglia-like cells reveal impaired amyloid plaque clearance upon heterozygous or homozygous loss of TREM2
By ACA |
Murine microglia expressing the Alzheimer's disease–linked TREM2R47H mutation display variable decrease in phagocytosis, while impaired phagocytosis is reported following loss ...
Read More A signature pattern of cortical atrophy in dementia with Lewy bodies: A study on 333 patients from the European DLB consortium
By ACA |
We explored regional brain atrophy patterns and their clinical correlates in dementia with Lewy bodies (DLB).
Read More Hypertension and obesity moderate the relationship between β-amyloid and cognitive decline in midlife
By ACA |
This study tested if central obesity, hypertension, or depressive symptoms moderated the relationship between β-amyloid (Aβ) and longitudinal cognitive performance ...
Read More AMYPAD Diagnostic and Patient Management Study: Rationale and design
By ACA |
Reimbursement of amyloid–positron emission tomography (PET) is lagging due to the lack of definitive evidence on its clinical utility and ...
Read More Withdrawn: Plasma concentrations of free amyloid-β cannot predict the development of Alzheimer’s disease
By ACA |
The Publisher regrets that this article is an accidental duplication of an article that has already been published, DOI of ...
Read More WITHDRAWN: Revisiting the cholinergic hypothesis in Alzheimer’s disease: Emerging evidence from translational and clinical research
By ACA |
This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this ...
Read More Whitepaper: Defining and investigating cognitive reserve, brain reserve, and brain maintenance
By ACA |
Several concepts, which in the aggregate get might be used to account for “resilience” against age- and disease-related changes, have ...
Read More Retinal signs and risk of incident dementia in the Atherosclerosis Risk in Communities study
By ACA |
The easily-imaged retinal microvasculature may reflect the brain microvasculature and therefore be related to dementia.
Read More