Primary age-related tauopathy (PART) and Alzheimer’s disease (AD)
By ACA |
Bell et al. [1] recently compared neuropathologic, genetic, and cognitive profiles in 40 primary age-related tauopathy (PART) and 130 Alzheimer's disease ...
Read More Detecting both current and prior Helicobacter pylori infection is important to assess its impact on dementia
By ACA |
We read with great interest the article written by Fani et al. on the association between Alzheimer's disease and Helicobacter pylori ...
Read More Brain arterial dilatation and the risk of Alzheimer’s disease
By ACA |
We tested the hypothesis that brain arterial dilatation increases the risk of Alzheimer's dementia (AD).
Read More Parkinsonism in MCI or mild Alzheimer’s disease
By ACA |
Examining 106 subjects aged 60-97 years, Sasaki [1] recently found parkinsonism (rigidity, resting tremor, reduced dopamine transporter in basal ganglia) in ...
Read More Emerging cerebrospinal fluid biomarkers in autosomal dominant Alzheimer’s disease
By ACA |
Four less well-studied but promising “emerging” cerebrospinal fluid (CSF) biomarkers are elevated in late-onset Alzheimer disease (AD): neurogranin, synaptosomal-associated protein-25 ...
Read More Failure to detect an association between self-reported traumatic brain injury and Alzheimer’s disease neuropathology and dementia
By ACA |
Recent research with neuropathologic or biomarker evidence of Alzheimer's disease (AD) casts doubt on traumatic brain injury (TBI) as a ...
Read More GeneMatch: A novel recruitment registry using at-home APOE genotyping to enhance referrals to Alzheimer’s prevention studies
By ACA |
Recruitment for Alzheimer's disease (AD) prevention research studies is challenging because of lack of awareness among cognitively healthy adults coupled ...
Read More Clinical and cortical decline in the aphasic variant of Alzheimer’s disease
By ACA |
Primary progressive aphasia (PPA) displays variable progression trajectories that require further elucidation.
Read More Learnings about the complexity of extracellular tau aid development of a blood-based screen for Alzheimer’s disease
By ACA |
The tau protein plays a central role in Alzheimer's disease (AD), and there is huge interest in measuring tau in ...
Read More Human stem cell–derived monocytes and microglia-like cells reveal impaired amyloid plaque clearance upon heterozygous or homozygous loss of TREM2
By ACA |
Murine microglia expressing the Alzheimer's disease–linked TREM2R47H mutation display variable decrease in phagocytosis, while impaired phagocytosis is reported following loss ...
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