Whitepaper: Defining and investigating cognitive reserve, brain reserve, and brain maintenance
By ACA |
Several concepts, which in the aggregate get might be used to account for “resilience” against age- and disease-related changes, have ...
Read More Retinal signs and risk of incident dementia in the Atherosclerosis Risk in Communities study
By ACA |
The easily-imaged retinal microvasculature may reflect the brain microvasculature and therefore be related to dementia.
Read More Quantitative proteomics reveals distinct composition of amyloid plaques in Alzheimer’s disease
By ACA |
We investigated the proteomic profiles of amyloid plaques (APs) from Alzheimer's disease (AD) and age-matched non-AD brains and APP/PS1 transgenic ...
Read More Longitudinal study of hearing loss and subjective cognitive function decline in men
By ACA |
We examined the relation between self-reported hearing loss, hearing aid use, and risk of subjective cognitive function (SCF) decline.
Read More Alzheimer’s disease and glaucoma: Look-alike neurodegenerative diseases
By ACA |
We read with great interest the article by Lee et al. [1] entitled “Associations between recent and established ophthalmic conditions and ...
Read More Early versus late MCI: Improved MCI staging using a neuropsychological approach
By ACA |
The Alzheimer's Disease Neuroimaging Initiative (ADNI) separates “early” and “late” mild cognitive impairment (MCI) based on a single memory test. ...
Read More Genetic origin of a large family with a novel PSEN1 mutation (Ile416Thr)
By ACA |
A small percentage of Alzheimer's disease (AD) cases are caused by genetic mutations with autosomal dominant inheritance. We report a ...
Read More Predicting diagnosis and cognition with 18F-AV-1451 tau PET and structural MRI in Alzheimer’s disease
By ACA |
The relative importance of structural magnetic resonance imaging (MRI) and tau positron emission tomography (PET) to predict diagnosis and cognition ...
Read More Artificially low mild cognitive impairment to normal reversion rate in the Alzheimer’s Disease Neuroimaging Initiative
By ACA |
We examined reasons for low mild cognitive impairment (MCI)-to-cognitively normal (CN) reversion rates in the Alzheimer's Disease Neuroimaging Initiative (ADNI).
Read More A rare missense variant of CASP7 is associated with familial late-onset Alzheimer’s disease
By ACA |
The genetic architecture of Alzheimer's disease (AD) is only partially understood.
Read More