Federal grant to help Mayo Clinic, collaborators advance multiethnic Alzheimer’s research

By ACA | March 28, 2023

Alzheimer’s disease affects people of all ethnic groups. Armed with $41 million in new federal funding, Mayo Clinic researchers and colleagues from 13 other institutions around the country are pursuing three multiethnic projects to identify targets for treatment.

Alzheimer’s disease robs victims of their memories and families of quality time with their loved ones. Deaths from Alzheimer’s more than doubled from 2000 to 2019, and the number of people living with the disease is expected to rise to 13 million by 2050, according to the Alzheimer’s Association.

The new research program seeks to identify the next generation of precision medicine biomarkers and potential novel therapeutic targets of Alzheimer’s disease and related dementias in multiethnic populations. The program, called Centrally-Linked Longitudinal Peripheral Biomarkers of AD in Multiethnic Populations (CLEAR-AD), will be funded by a five-year grant from the National Institute on Aging, part of the National Institutes of Health. The grant is expected to total $41 million.

Nilüfer Ertekin-Taner, M.D., Ph.D., a Mayo Clinic professor of neuroscience and neurology and a physician-scientist, will lead this program with co-principal investigators Minerva Carrasquillo, Ph.D., a Mayo neuroscientist, and the Indiana University School of Medicine’s Andrew Saykin, PsyD., and Kwangsik Nho, Ph.D.
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